
Xylazine hydrochloride
CAS No. 23076-35-9
Xylazine hydrochloride( —— )
Catalog No. M13646 CAS No. 23076-35-9
Xylazine Hydrochloride is α2 class of adrenergic receptor agonist.
Purity : >98% (HPLC)






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Biological Information
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Product NameXylazine hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionXylazine Hydrochloride is α2 class of adrenergic receptor agonist.
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DescriptionXylazine Hydrochloride is α2 class of adrenergic receptor agonist.(In Vivo):Xylazine (5.2 mg/kg; intraperitoneal injection; for 10-60 minutes; male Sprague-Dawley rats) administration alters mRNA expression and protein phosphorylation levels of AMPK signaling molecules, suggesting that the LKB1-AMPK pathway plays a role in the sedative and tranquilizing effects in the CNS caused by Xylazine treatment.
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In Vitro——
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In VivoXylazine (5.2 mg/kg; intraperitoneal injection; for 10-60 minutes; male Sprague-Dawley rats) administration alters mRNA expression and protein phosphorylation levels of AMPK signaling molecules, suggesting that the LKB1-AMPK pathway plays a role in the sedative and tranquilizing effects in the CNS caused by Xylazine treatment. Animal Model:Male Sprague-Dawley rats (160-180 g)Dosage:5.2 mg/kg Administration:Intraperitoneal injection; for 10 minutes, 20 minutes, 40 minutesor 60 minutes Result:Increased in AMPK activity in the cerebral cortex, hippocampus, thalamus and cerebellum. Phosphorylated LKB1 and AMPKα protein levels were decreased.
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetAdrenergic Receptor
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Recptorα-adrenergic receptor
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number23076-35-9
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Formula Weight256.79
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Molecular FormulaC12H16N2S·HCl
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Purity>98% (HPLC)
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SolubilityEthanol: 50 mg/mL (194.71 mM); Water: 12 mg/mL (46.73 mM); DMSO: 50 mg/mL (194.71 mM)
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SMILESCl.CC1=CC=CC(C)=C1NC1=NCCCS1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ambrisko TD, et al. Can J Vet Res,2002, 66(1), 42-49.
molnova catalog



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